Pulpectomy with CTZ paste in a patient with sickle cell disease. Case report
DOI:
https://doi.org/10.24265/a7nr2f48Keywords:
Anemia, Sickle cell; Caries; Pulpectomy; Dental Pulp; NecrosisAbstract
The aim of this clinical report case was to perform non-instrumental pulp therapy with CTZ in temporary dental organs in a patient with sickle cell disease (SCD). Female 5 years 7 months old, diagnosed with SCD was treated at Regional Hospital of High Speciality of the Child “Dr. Rodolfo Nieto Padrón” in the pediatric dentistry area. At the clinical observation presented tendons and conjunctival palidity, at the intraoral level presented mucous pallidity, hypomineralization, caries in various dental organs (DO), the results of blood biometry were a hemoglobin: 6.04 g/dl, erythrocytes: 1.82 g/ dl, leukocytes : 15 450 x 103/µL. Dental diagnosis was early childhood caries and pulpar necrosis in temporary molars 64 and 85 the first with dentoalveolar abscess. Non-instrumental pulp therapy treatment was carried out with CTZ in both temporary molars with pulp necrosis and as temporary glass ionomer restoration and subsequently steel crowns, temporary obturations in different DO for caries lesions. Result of CTZ treatment was effective, showing clinical and radiographic improvements. Non-instrumental pulp therapy with CTZ is a viable, fast and safe effective treatment in patients with SCD, prevents bacterial spread to periodontal tissues and minimizes systemic risk.
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Kakkar M, Holderle K, Sheth M, Arany S, Schiff L, Planerova A. Orofacial Manifestation and Dental Management of Sickle Cell Disease: A Scoping Review. Anemia. 2021;2021:5556708.
Ngawha TU, Nweke M, Ezigbo ED. Contributions of von Willebrand factor to clinical severity of sickle cell disease: a systematic review and metanalysis. Hematology. 2022;27(1):860-866.
Rivera-Salinas P, Rueda-Ventura MA, Isidro-Olán LB, Zurita-Zarracino E. Manifestations in Patients with Hereditary Hemolytic Anemias. Rev Hematol Mex. 2021;22(2):69-79.
Acharya B, Mishra DP, Barik B, Mohapatra Rk, Sarangi Ak. Recent Progress in the Treatment of Sickle Cell Disease: an up-to-date review. Beni Suef Univ J Basic Appl Sci. 2023;12(38):1-18.
Egesa WI, Nakalema G, Waibi WM, Turyasiima M, Amuje E, Kiconco G, et al. Sickle cell Disease in Children and Adolescents: A Review of the Historical, Clinical, and Public Health Perspective of Sub-Saharan Africa and Beyond. Int J Pediatr. 2022;2022:3885979.
Sendrak A, Kondamudi NP. Sickle Cell Disease. En: StatPearls [Internet]. Treasure Island (FL). 2023 Jan. [citado el 20 de Octubre del 2023]. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK482384/
Brandow AM, Liem RI. Advances in the diagnosis and treatment of sickle cell disease. J Hematol Oncol. 2022;15(1):20.
Portilla Cárdenas MD, Castañeda Hernández RE, Deschamps Lago RA, Deschamps Lago ME, Salazar Calderón ME, Gónzalez Aguilar A. Detección de Hemoglobina “S” por inducción de drepanocitos en pacientes del Hospital de Alta Especialidad de Veracruz. Rev Invest Cien Sal. 2020;15(1):76-78.
Brousse V, Bernaudin F, Melaine A, Goguillot M, Gallagher M, Benard S. Severity and burden of sickle cell disease in France: a nationwide real-world study. Haematologica. 2023;108(9):2476-2486.
Aulestia-Vieran PV, Cardoso Alves ID, Moura Chicrala G, Silva Santos PS, Valente Soares Junior LA. Manejo odontológico del paciente con anemia falciforme: revisión integrativa. Odontología. 2022;22(2):92-107.
Zúñiga CP, Martínez GC, González RL, Rendón CD, Rojas RN, Barriga CF. Enfermedad de células falciformes: Un diagnóstico para tener presente. Rev Chil Pediatr. 2018;89(4):525-529.
Carden MA, Little J. Emerging disease-modifying therapies for sickle cell disease. Haematologica. 2019;104(9):1710-1719.
Darbari DS, Sheehan VA, Ballas SK. The vaso- occlusive pain crisis in sickle disease: Definition, pathophysiology, and management. Eur J Haematol. 2020;105(3):237-246.
Assinger A, Buchberger E, Laky M, Esfandeyari A, Brostjan C, Volf I. Periodontopathogens induce soluble P-selectin release by endothelial cells and platelets. Thromb Res. 2011;27(1):e20-6.
Ayala Viloria AJ, González Torres HJ, David Tarud GJ. Anemia de células falciformes: una revisión. Revista Científica Salud Uninorte. 2016;32(3):513- 527.
Bhat A, Ramalingam K, Syed W, Adawi A. Oral Findings in Sickle Cell Anemia in Patient-A: Case Report. Case Reports in Odontology. 2021;8(2):20- 23.
Palomer R Leonor. Caries dental en el niño. Una enfermedad contagiosa. Rev Chil Pediatr. 2006;77(1):56-60.
Yue H, Xu X, Liu Q, Li X, Jiang W, Hu B. Association between sickle cell disease and dental caries: a systematic review and meta-analysis. Hematology, 2020;25(1):309-319.
NN Soni. Microradiographic study of dental tissues in sickle-cell anaemia. Archives of Oral Biology. 1966;11(6):561–564.
Luchtman-Jones L, Pressel S, Hilliard L, Brown RC, Smith MG, Thompson AA. Effects of hydroxyurea treatment for patients with hemoglobin SC disease. Am J Hematol. 2016;91(2):238-242.
Eleftherou D, Arhakis A, Davidopoulou S. Sickle Cell Disease: An Overview of Oral Health Considerations for Pediatric Patients. European Journal of Dental and Oral Health. 2021;2(3):9-17.
Brandão CF, Oliveira VMB, Santos ARRM, da Silva TMM, Vitella VQC, Simas GGPP, et al. Association between sickle cell disease and the oral health condition of children and adolescents. BMC Oral Health. 2018;18:(1):169.
Da Fonseca M, Oueis HS, Casamassimo PS. Sickle cell anemia: a review for the pediatric dentist. Pediatr Dent. 2007;29(2):159-169.
Mulimani P, Ballas SK, Abas AB, Karanth L. Treatment of dental complications in sickle cell disease. Cochrane Database of Systematic Reviews. 2019;12(12):CD011633.
Jiménez Juárez EA, Gallegos Ramírez A, Rueda Ventura MA, Ramírez Mendoza J. Efectividad entre la pasta CTZ y Ultrapextm en molares necróticos de niños que acuden a la Clínica de Odontología infantil UJAT. Rev Tamé. 2017;6(17):609-611.
Garrocho Rangel A, Jalomo Ávila C, Rosales Berber MÁ. Pozos Guillén A. Lesion Sterilization Tissue Repair (LSTR) Approach Of Non-Vital Primary Molars With A Chloramphenicol-Tetracycline-ZOE Antibiotic Paste: A Scoping Review. J Clin Pediatr Dent. 2021;45(6):369-375.
Ferreira SB, Tavares WL, Rosa MA, Brito LC, Vieira LQ, Martelli H Júnior, et al. Sickle cell anemia in Brazil: personal, medical and endodontic patterns. Braz Oral Res. 2016;30(1):S1806-83242016000100255.
Moura J, Lima M, Nogueira N, Castro M, Lima C, Moura M, et al. LSTR Antibiotic Paste Versus Zinc Oxide and Eugenol Pulpectomy for the Treatment of Primary Molars with Pulp Necrosis: A Randomized Controlled Trial. Pediatr Dent. 2021;43(6):435-442.
Manes Uribe C, Mejía JD, Restrepo M. Técnica LSTR con pasta CTZ para el tratamiento de la necrosis pulpar en molares primarios. Reporte de caso. Revista de Odontopediatría Latinoamericana. 2023;13(0):e-224568.
Selvakumar G, Raveendran A, Swathika B, Ganesan S, Prem Kumar E, Sanyal GC. Evaluation of the Anti- microbial Efficacy of a Novel Endodontic Irrigant Against Enterococcus faecalis: An In Vitro Study. Cureus. 2023;15(10):e46410.
Rayos-Verdugo JY, Rivera-Chaparro F, Castro-Salazar GY, Ramírez Álvarez M, Romero Quintana JG, Loyola Rodríguez JP. Propylene Glycol Potentiates the Inhibitory Action of CTZ Paste on Antibiotic-Resistant Enterococcus faecalis Isolated from the Root Canal: An In Vitro Study. Microorganisms. 2023;11(9):2208.
Sarhan De-Lima N, Roth Matos L, Barretos Matos D, De Lima Dantas JB, Rabelo Torregrossa V. Extensive palatal swelling and asymptomatic pulp necrosis in a patient with sickle cell trait: A new case report. J Oral Diag. 2021;6(2):e20210017.
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