Frequency of affected teeth in pediatric patients with molar hypomineralisation

Authors

DOI:

https://doi.org/10.24265/w9kvc745

Keywords:

Molar Hypomineralization; Pediatric Dentistry; Permanent Dentition

Abstract

Molar hypomineralisation (MH) was defined as a systemic pathology that affects one or all of the first permanent molars, often involving incisors. Objectives: To estimate the frequency of affected teeth in patients with MH who attended the Faculty of Dentistry University of Buenos Aires. Materials and Methods: An observational, cross-sectional, and descriptive study was conducted on children with complete dentition who received treatment at the Pediatric Department April-August 2024. Faculty members performed clinical diagnoses with a Kappa value of 0.87, using the Mathu-Muju and Wright criteria. Recorded data included sex, age, presence of MH, and tooth severity levels, analyzed through means, percentages, and odds ratio. Results: The study comprised 173 patients, mean age of 14±1.6 years, 58.39% female. Among the participants, 27.74% (CI 21.35-35.14) had MH, mean age 13.54±1.86 years and 66.7% being female. Lesions were observed across all dental groups. First permanent molars were affected in 54.69% of cases (CI 47.34-61.89), followed by incisors at 17.26% (CI 13.63-21.42), second molars at 12.5% (CI 8.16-18.04), first premolars and canines at 10.94% (CI 6.89-16.25), and second premolars at 8.85% (CI 5.23-13.81). Of the lesions observed, 87.84% were classified as mild, 8.23% as moderate, and severe lesions were identified only in the first (1.96%) and second molars (1.96%). Upper incisors were found to be more affected than lower incisors (OR 5.38). Conclusions: In this sample, although the first molars and incisors were the most affected, all dental groups displayed lesions, with the second molars showing the highest frequency.

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Author Biographies

  • Ana María Biondi , Universidad de Buenos Aires, Facultad de Odontología, Cátedra Odontología Integral Niños.

    Magister en odontología

  • Silvina Gabriela Cortese , Universidad de Buenos Aires, Facultad de Odontología, Cátedra Odontología Integral Niños

    Doctora en odontología

  • Jimena Alejandra Anchava, Universidad de Buenos Aires, Facultad de Odontología, Cátedra Odontología Integral Niños

    Especialista en Odontopediatría

References

Oromí Duricha J. Enfermedades emergentes y reemergentes: algunas causas y ejemplos. Medicina Integral. 2000,36(3):79-82.

Shields S, Chen T, Crombie F, Manton DJ, Silva M. The Impact of Molar Incisor Hypomineralisation on Children and Adolescents: A Narrative Review. Healthcare (Basel). 2024,12(3):370. doi: 10.3390/healthcare12030370.

Weerheijm KL, Jälevik B, Alaluusua S. Molar-incisor hypomineralisation. Caries Res. 2001;35 390-391. doi: 10.1159/000047479

Weerheijm KL. Molar incisor hypomineralisation (MIH). Eur J Paediatr Dent. 2003;4(3):114-20.

Childers NK, Hubbard MJ. Adopting The D3 Group’s translational paradigm for molar hypomineralization and chalky teeth. Pediatr Dent. 2024;46 (5):302-304.

Mathu-Muju K, Wright JT. Diagnosis and treatment of molar incisor hypomineralization. Compend Contin Educ Dent. 2006; 27(11):604-10.

Lygidakis NA, Garot E, Somani C, Taylor GD, Rouas P, Wong FSL. Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document. Eur Arch Paediatr Dent. 2022;23(1):3-21. doi: 10.1007/s40368-021-00668-5.

Elfrink ME, Schuller AA, Weerheijm KL, Veerkamp JS. Hypomineralized second primary molars: prevalence data in dutch 5-year-olds. Caries Res. 2008; 42:282-285. doi: 10.1159/000135674.

Garot E, Denis A, Delbos Y, Manton D, Silva M, Rouas P. Are hypomineralised lesions on second primary molars (HSPM) a predictive sign of molar incisor hypomineralisation (MIH)? A systematic review and a meta-analysis. J Dent. 2018;72: 8-13.doi: 10.1016/j.jdent.2018.03.005.

De Farias AL, Rojas–Gualdrón DF, Girotto Bussaneli D, Santos-Pinto L, Mejía JD, Restrepo M. Does molar-incisor hypomineralization (MIH) affect only permanent first molars and incisors? New observations on permanent second molars. Int J Paediatr Dent. 2022;32:1–10. doi: 10.1111/ipd.12780

Bussaneli DG, Vieira AR, Santos-Pinto L, Restrepo M, Kevrekidou A, Kosma I, Kotsanos I, Arapostathis KN, Kotsanos N. Enamel opacities in all other than Molar Incisor Hypomineralisation index teeth of adolescents. Int J Paediatr Dent. 2021;31(2):270-7. doi: 10.1111/ipd 12735.

Mittal N. Phenotypes of enamel hypomineralization and molar incisor hypomineralization in permanent dentition: identification, quantification and proposal for classification. J Clin Pediatr Dent. 2016;40(5):367-74. doi: 10.17796/1053-4628-40.5.367.

Elfrink M. De eerste 1.000 dagen van een kaasmolaar [The first 1,000 days in molar-incisor hypomineralization and hypomineralized second primary molars]. Ned Tijdschr Tandheelkd. 2025;4;132(3):124-129. doi: 10.5177/ntvt.2025.03.24121.

Padavala S; Sukumaran G. Molar incisor hypomineralization and its prevalence. Contemp Clin Dent. 2018; 9(Suppl 2): S246-S250. doi: 10.4103/ccd.ccd_161_18.

Silva MJ, Scurrah KJ, Craig JM, Manton DJ, Kilpatrick N. Etiology of molar incisor hypomineralization – a systematic review. Community Dent Oral Epidemiol. 2016;44:342-353. doi: 10.1111/cdoe.12229.

Vieira AR, Kup E. On the etiology of molar-incisor hypomineralization. Caries Res. 2016;50:166-169. doi: 10.1159/000445128.

Alzahrani AY, Alamoudi NMH, El Meligy, OAES. Contemporary understanding of the etiology and management of molar incisor hypomineralization: a literature review. Dent. J. 2023;11(7):157. doi.org/10.3390/dj11070157

Hubbard MJ, Mangum JE, Perez VA, Williams R. A breakthrough in understanding the pathogenesis of molar hypomineralisation: the mineralisation-poisoning model. Front Physiol. 2021; 21; 12:802833. doi: 10.3389/fphys.2021.

Pérez V, Mangum J, Hubbard M. Pathogenesis of molar hypomineralisation: aged albumin demarcates chalky regions of hypomineralised enamel. Front Physiol. 2020;30;11:579015. doi: 10.3389/fphys.2020.579015.

Williams R, Pérez Vidal A., Mangum J, Hubbard M. Pathogenesis of molar hypomineralisation: hypomineralised 6-year molars contain traces of fetal serum albumin. Front Physiol; 2020;11:619. doi: 10.3389/fphys.2020.00619.

Hubbard M, Pérez Vidal A, Ganss B. 100 Years of chalky teeth research: from pioneering histopathology to social good. Front. Dent. Med. 2021;(1):632534. doi:10.3389/fdmed.2020.632534

Biondi AM, Cortese SG, Martínez K, Ortolani AM, Sebelli PM, Ienco M, et al. Prevalence of molar incisor hypomineralization in the city of Buenos Aires. Acta Odontol Latinoam. 2011;24(1):81-5.

Zhao D, Dong B, Yu D, Ren Q, Sun Y. The prevalence of molar incisor hypomineralization: evidence from 70 studies. Int. J. Paediatr. Dent. 2018;28(2):170-179 doi: 10.1111/ipd.12323

Malini, V. Molar Incisor hypomineralization a review. J Dental Sci. 2019;4(1):000216. doi: 10.23880/oajds-16000216.

Schmalfuss A, Stenhagen KR, Tveit AB, Crossner CG, Espelid I. Canines are affected in 16-year-olds with molar-incisor hypomineralisation (MIH): an epidemiological study based on the Tromsø study: "Fit Futures". Eur Arch Paediatr Dent. 2016;17(2):107-13. doi: 10.1007/s40368-015-0216-6.

Biondi AM, Córtese SG, Babino L, Toscano MA. Molar incisor hypomineralization: analysis of asymmetry of lesions. Acta Odontol Latinoam. 2019;32(1):44-48.

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Published

2026-04-30

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Artículos Originales/ Original articles

How to Cite

1.
Biondi AM, Cortese SG, Anchava JA. Frequency of affected teeth in pediatric patients with molar hypomineralisation. kiru [Internet]. 2026 Apr. 30 [cited 2026 May 5];23(2):118-23. Available from: https://portalrevistas.aulavirtualusmp.pe/index.php/Rev-Kiru0/article/view/3455

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